Power Analysis for Genetic Association Test (PAGEANT) provides insights to challenges for rare variant association studies

We propose a new method for power calculation of aggregate level association rare variants tests. Compared to traditional power cacualtion, the new methods require a small number of key paprameters. We develop an analytic framework to obtain bounds …

Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study

This is the first GWAS of gallbladder cancer in India. We identified several genome-wide significant associations for several markers in the chromosomal region 7q21.12 harbouring both the *ABCB1* and *ABCB4* genes.